Glycoproteomic profiling of serum-derived small extracellular vesicles enriched via ultracentrifugation and affinity-based techniques

Glycoproteomic profiling of serum-derived small extracellular vesicles enriched via ultracentrifugation and affinity-based techniques

Abstract Small extracellular vesicles (sEVs) are gaining recognition as potential biomarkers for diseases, including cancer, due to their involvement in key pathophysiological processes. However, the glycosylation of EVs and the specific roles of their glycans remain poorly understood. While several...

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Bibliographic Details
Main Authors: Mojibola Fowowe, Cristian D. Gutierrez Reyes, Judith Nwaiwu, Joy Solomon, Oluwatosin Daramola, Sherifdeen Onigbinde, Joseph Andrew Whitley, Houjian Cai, Yehia Mechref
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Small extracellular vesicles
EVs
Immunoaffinity capture
Ultracentrifugation
Glycoproteomics
Proteomics
Online Access:https://doi.org/10.1038/s41598-025-05430-1
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https://doi.org/10.1038/s41598-025-05430-1

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