Enhancing Clinical Decision Making by Predicting Readmission Risk in Patients With Heart Failure Using Machine Learning: Predictive Model Development Study

Abstract BackgroundPatients with heart failure frequently face the possibility of rehospitalization following an initial hospital stay, placing a significant burden on both patients and health care systems. Accurate predictive tools are crucial for guiding clinical decision-ma...

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Main Authors: Xiangkui Jiang, Bingquan Wang
Format: Article
Language:English
Published: JMIR Publications 2024-12-01
Series:JMIR Medical Informatics
Online Access:https://medinform.jmir.org/2024/1/e58812
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author Xiangkui Jiang
Bingquan Wang
author_facet Xiangkui Jiang
Bingquan Wang
author_sort Xiangkui Jiang
collection DOAJ
description Abstract BackgroundPatients with heart failure frequently face the possibility of rehospitalization following an initial hospital stay, placing a significant burden on both patients and health care systems. Accurate predictive tools are crucial for guiding clinical decision-making and optimizing patient care. However, the effectiveness of existing models tailored specifically to the Chinese population is still limited. ObjectiveThis study aimed to formulate a predictive model for assessing the likelihood of readmission among patients diagnosed with heart failure. MethodsIn this study, we analyzed data from 1948 patients with heart failure in a hospital in Sichuan Province between 2016 and 2019. By applying 3 variable selection strategies, 29 relevant variables were identified. Subsequently, we constructed 6 predictive models using different algorithms: logistic regression, support vector machine, gradient boosting machine, Extreme Gradient Boosting, multilayer perception, and graph convolutional networks. ResultsThe graph convolutional network model showed the highest prediction accuracy with an area under the receiver operating characteristic curve of 0.831, accuracy of 75%, sensitivity of 52.12%, and specificity of 90.25%. ConclusionsThe model crafted in this study proves its effectiveness in forecasting the likelihood of readmission among patients with heart failure, thus serving as a crucial reference for clinical decision-making.
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institution Kabale University
issn 2291-9694
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spelling doaj-art-d5100d6692264da594b33e0025e362832025-01-07T20:31:32ZengJMIR PublicationsJMIR Medical Informatics2291-96942024-12-0112e58812e5881210.2196/58812Enhancing Clinical Decision Making by Predicting Readmission Risk in Patients With Heart Failure Using Machine Learning: Predictive Model Development StudyXiangkui Jianghttp://orcid.org/0000-0002-7245-770XBingquan Wanghttp://orcid.org/0009-0004-4382-8198 Abstract BackgroundPatients with heart failure frequently face the possibility of rehospitalization following an initial hospital stay, placing a significant burden on both patients and health care systems. Accurate predictive tools are crucial for guiding clinical decision-making and optimizing patient care. However, the effectiveness of existing models tailored specifically to the Chinese population is still limited. ObjectiveThis study aimed to formulate a predictive model for assessing the likelihood of readmission among patients diagnosed with heart failure. MethodsIn this study, we analyzed data from 1948 patients with heart failure in a hospital in Sichuan Province between 2016 and 2019. By applying 3 variable selection strategies, 29 relevant variables were identified. Subsequently, we constructed 6 predictive models using different algorithms: logistic regression, support vector machine, gradient boosting machine, Extreme Gradient Boosting, multilayer perception, and graph convolutional networks. ResultsThe graph convolutional network model showed the highest prediction accuracy with an area under the receiver operating characteristic curve of 0.831, accuracy of 75%, sensitivity of 52.12%, and specificity of 90.25%. ConclusionsThe model crafted in this study proves its effectiveness in forecasting the likelihood of readmission among patients with heart failure, thus serving as a crucial reference for clinical decision-making.https://medinform.jmir.org/2024/1/e58812
spellingShingle Xiangkui Jiang
Bingquan Wang
Enhancing Clinical Decision Making by Predicting Readmission Risk in Patients With Heart Failure Using Machine Learning: Predictive Model Development Study
JMIR Medical Informatics
title Enhancing Clinical Decision Making by Predicting Readmission Risk in Patients With Heart Failure Using Machine Learning: Predictive Model Development Study
title_full Enhancing Clinical Decision Making by Predicting Readmission Risk in Patients With Heart Failure Using Machine Learning: Predictive Model Development Study
title_fullStr Enhancing Clinical Decision Making by Predicting Readmission Risk in Patients With Heart Failure Using Machine Learning: Predictive Model Development Study
title_full_unstemmed Enhancing Clinical Decision Making by Predicting Readmission Risk in Patients With Heart Failure Using Machine Learning: Predictive Model Development Study
title_short Enhancing Clinical Decision Making by Predicting Readmission Risk in Patients With Heart Failure Using Machine Learning: Predictive Model Development Study
title_sort enhancing clinical decision making by predicting readmission risk in patients with heart failure using machine learning predictive model development study
url https://medinform.jmir.org/2024/1/e58812
work_keys_str_mv AT xiangkuijiang enhancingclinicaldecisionmakingbypredictingreadmissionriskinpatientswithheartfailureusingmachinelearningpredictivemodeldevelopmentstudy
AT bingquanwang enhancingclinicaldecisionmakingbypredictingreadmissionriskinpatientswithheartfailureusingmachinelearningpredictivemodeldevelopmentstudy