A top‐down systems biology view of microbiome‐mammalian metabolic interactions in a mouse model

A top‐down systems biology view of microbiome‐mammalian metabolic interactions in a mouse model

Abstract Symbiotic gut microorganisms (microbiome) interact closely with the mammalian host's metabolism and are important determinants of human health. Here, we decipher the complex metabolic effects of microbial manipulation, by comparing germfree mice colonized by a human baby flora (HBF) or...

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Main Authors: François‐Pierre J Martin, Marc‐Emmanuel Dumas, Yulan Wang, Cristina Legido‐Quigley, Ivan K S Yap, Huiru Tang, Séverine Zirah, Gerard M Murphy, Olivier Cloarec, John C Lindon, Norbert Sprenger, Laurent B Fay, Sunil Kochhar, Peter van Bladeren, Elaine Holmes, Jeremy K Nicholson
Format: Article
Language:English
Published: Springer Nature 2007-05-01
Series:Molecular Systems Biology
Subjects:
co‐metabolism
gut microflora
metabonomics/metabolomics
network modeling
systems biology
Online Access:https://doi.org/10.1038/msb4100153
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https://doi.org/10.1038/msb4100153

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