Activated B cells suppress T-cell function through metabolic competition

Activated B cells suppress T-cell function through metabolic competition

Background B cells play a pivotal role in regulating the immune response. The induction of B cell-mediated immunosuppressive function requires B cell activating signals. However, the mechanisms by which activated B cells mediate T-cell suppression are not fully understood.Methods We investigated the...

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Main Authors: Li Li, Michael Green, Fang Wang, Ye Li, Jennifer Wargo, Marina Konopleva, Elizabeth J Shpall, Rafet Basar, May Daher, Ana Karen Nunez Cortes, Hila Shaim, Natalia Baran, Ken Chen, Luis Muniz-Feliciano, Nobuhiko Imahashi, Yuefan Huang, Pinaki Prosad Banerjee, Junjun Lu, Nadima Uprety, Emily Ensley, Tamara J Laskowski, Judy S Moyes, Mayela Mendt, Lucila N Kerbauy, Mayra Shanley, Francesca Lorraine Wei Inng Lim, Katayoun Rezvani
Format: Article
Language:English
Published: BMJ Publishing Group 2022-12-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/10/12/e005644.full
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https://jitc.bmj.com/content/10/12/e005644.full

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