Fighting vessel dysmorphia to improve glioma chemotherapy

Abstract High‐grade gliomas are aggressive and abundantly vascular tumors, and as in most cancer types, blood vessels in advanced lesions are highly abnormal. Poor perfusion and vascular leakage in tumor tissue resulting in hypoxia, necrosis, and high interstitial fluid pressure can hamper the effic...

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Bibliographic Details
Main Authors: Marja Lohela, Kari Alitalo
Format: Article
Language:English
Published: Springer Nature 2017-11-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.15252/emmm.201708431
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