Non-lytic spread of poliovirus requires the nonstructural protein 3CD

Non-lytic spread of poliovirus requires the nonstructural protein 3CD

ABSTRACT Non-enveloped viruses like poliovirus (PV) have evolved the capacity to spread by non-lytic mechanisms. For PV, this mechanism exploits the host secretory autophagy pathway. Virions are selectively incorporated into autophagosomes, double-membrane vesicles that travel to the plasma membrane...

Full description

Saved in:
Bibliographic Details
Main Authors: David Aponte-Diaz, Jayden M. Harris, Tongjia Ella Kang, Victoria Korboukh, Mohamad S. Sotoudegan, Jennifer L. Gray, Neela H. Yennawar, Ibrahim M. Moustafa, Andrew Macadam, Craig E. Cameron
Format: Article
Language:English
Published: American Society for Microbiology 2025-01-01
Series:mBio
Subjects:
poliovirus
autophagy
non-lytic spread
enterovirus
replication organelles
cell membranes
Online Access:https://journals.asm.org/doi/10.1128/mbio.03276-24
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://journals.asm.org/doi/10.1128/mbio.03276-24

Similar Items