Knockout of the sulfide: quinone oxidoreductase SQR reduces growth of HCT116 tumor xenograft

Colorectal cancer (CRC) exhibits significant diversity and heterogeneity, posing a requirement for novel therapeutic targets. Polysulfides are associated with CRC progression and immune evasion, but the underlying mechanisms are not fully understood. Sulfide: quinone oxidoreductase (SQR), a mitochon...

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Bibliographic Details
Main Authors: Ting Lu, Qingda Wang, Yuping Xin, Xiaohua Wu, Yang Wang, Yongzhen Xia, Luying Xun, Huaiwei Liu
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Redox Biology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725001636
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