Prediction of the 70-gene signature (MammaPrint) high versus low risk by nomograms among axillary lymph node positive (LN+) and negative (LN-) Chinese breast cancer patients, a retrospective study

Prediction of the 70-gene signature (MammaPrint) high versus low risk by nomograms among axillary lymph node positive (LN+) and negative (LN-) Chinese breast cancer patients, a retrospective study

Abstract Background Luminal-type breast cancer (BC) was characterized as hormonal receptor positive human epidermal receptor 2 negative (HR+/HER2-). The 70-gene signature (70-GS, MammaPrint) test is recommended for assessing recurrence risk and guiding adjuvant chemotherapy decisions for Luminal-typ...

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Main Authors: Jie Lian, Ru Yao, Ying Xu, Linjuan Tan, Fangyuan Chen, Jiahui Zhang, Yang Qu, Lu Gao, Yanna Zhang, Songjie Shen, Qingli Zhu, Xinyu Ren, Lingyan Kong, Bo Pan, Qiang Sun, Yidong Zhou
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Cancer
Subjects:
Breast cancer
70-gene signature (MammaPrint)
Lymph node positive
Lymph node negative
Nomogram
Risk prediction
Online Access:https://doi.org/10.1186/s12885-025-14507-z
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https://doi.org/10.1186/s12885-025-14507-z

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