Exploratory insights from the immuno-oncology hollow fiber assay: A pilot approach bridging In Vitro and In Vivo models

Exploratory insights from the immuno-oncology hollow fiber assay: A pilot approach bridging In Vitro and In Vivo models

To facilitate the translation of immunotherapies from bench to bedside, predictive preclinical models are essential. We developed the in vivo immuno-oncology Hollow Fiber Assay (HFA) to bridge the gap between simpler cell-based in vitro assays and more complex mouse models for immuno-oncology drug e...

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Bibliographic Details
Main Authors: Tove Selvin, Malin Berglund, Anders Åkerström, Marco Zia, Jakob Rudfeldt, Malin Jarvius, Rolf Larsson, Claes R Andersson, Mårten Fryknäs
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:SLAS Technology
Subjects:
Immuno-oncology
Preclinical modeling
Mouse models
Hollow fibers
Online Access:http://www.sciencedirect.com/science/article/pii/S2472630324001146
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