Cardamom extract alleviates tamoxifen-induced liver damage by suppressing inflammation and pyroptosis pathway

Cardamom extract alleviates tamoxifen-induced liver damage by suppressing inflammation and pyroptosis pathway

Abstract Tamoxifen (TAM) is extensively used to manage estrogen receptor-positive breast cancer. Despite its effectiveness, its administration can negatively impact various organs, including the liver. This research focused on the effects of TAM on the pyroptotic pathway in the liver and evaluated t...

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Bibliographic Details
Main Authors: Wedad S. Sarawi, Hala A. Attia, Afraa Alzoubi, Nour Alanazi, Raeesa Mohammad, Rehab A. Ali
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Tamoxifen
Cardamom extract
Liver damage
CD68
Liver inflammation
Pyroptosis
Online Access:https://doi.org/10.1038/s41598-025-89091-0
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