Regulation of ADAM10 activity through microdomain-dependent intracellular calcium changes

Abstract A disintegrin and metalloproteinases (ADAMs) are transmembrane proteases that cleave other proteins close to the surface in a process called shedding. The prominent member ADAM10 has been linked to several pathologies such as Alzheimer’s disease, bacterial infection, cancer development and...

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Bibliographic Details
Main Authors: Federico Guillermo Gharzia, Ahmad Aljohmani, Andreas Beck, Stephan E. Philipp, Daniela Yildiz
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-024-01891-5
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