Human chromatin remodelers regulating HIV-1 transcription: a target for small molecule inhibitors

Abstract HIV-1 can establish a lifelong infection by incorporating its proviral DNA into the host genome. Once integrated, the virus can either remain dormant or start active transcription, a process governed by the HIV Tat protein, host transcription factors and the chromatin landscape at the integ...

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Bibliographic Details
Main Authors: Yuan Ma, Chuan Li, Susana Valente
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:https://doi.org/10.1186/s13072-025-00582-w
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