Human T follicular helper cells and their impact on IgE and IgG4 production across allergy, malignancy, and IgG4-related disease

Human T follicular helper cells and their impact on IgE and IgG4 production across allergy, malignancy, and IgG4-related disease

Human T follicular helper (Tfh) cells play a crucial role in orchestrating B cell differentiation, maturation, and immunoglobulin class switching. Recent studies have underscored the presence of Bcl-6 + Tfh cells not only in secondary lymphoid organs but also within tertiary lymphoid structures at i...

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Bibliographic Details
Main Authors: Mitsuhiro Akiyama, Waleed Alshehri, Sho Ishigaki, Koichi Saito, Yuko Kaneko
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Allergology International
Subjects:
Allergy
IgE
IgG4
IgG4-related disease
Malignancy
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893024000789
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