Cellular Entry, Cytotoxicity, and Antifungal Activity of Newly Synthesized Dendrimers

Cellular Entry, Cytotoxicity, and Antifungal Activity of Newly Synthesized Dendrimers

Dendrimers, 4-dimethylamino-1,8-naphthalimide (DAB) and its halogenated analog 3-bromo-4-dimethylamino-1,8-naphthalimide (DAB-Br), were evaluated on eukaryotic cells, human HFF-1 fibroblast cells, and five fungal species. Although both dendrimers have demonstrated antibacterial and antiviral potenti...

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Main Authors: Aneliya Kostadinova, Ema Gaydarska, Tanya Topouzova-Hristova, Dayana Benkova, Galya Staneva, Ekaterina Krumova, Rusina Hazarosova, Miroslav Marinov, Asya Tsanova, Albena Jordanova, Ivo Grabchev
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Applied Sciences
Subjects:
dendrimers
HFF-1 cell line
fungi
cytotoxicity
antifungal agents
Online Access:https://www.mdpi.com/2076-3417/15/14/7764
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