Descending projection neurons in the primary sensorimotor cortex regulate neuropathic pain and locomotion in mice

Abstract Cortical descending modulation of sensory processing in the spinal cord has been revealed, the role of cortico-brainstem projections in sensory and motor regulation remains poorly investigated. Here, we identified two previously unappreciated subpopulations in the primary sensorimotor corte...

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Bibliographic Details
Main Authors: Guo-Hong Wang, Xin-Yu Hou, Hui-Zhu Liu, Zi-Rui Zhou, Su-Su Lv, Lan-Xing Yi, Hui Li, Yu-Qiu Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61164-8
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