The emerging role of mitochondria in the pharmacological and toxicological effects of Tripterygium wilfordii Hook F: functions, targets and new therapeutic applications

Abstract Tripterygium wilfordii Hook F (TWHF) is a traditional Chinese medicine with multifaceted pharmacological properties, has faced clinical application challenges due to its dose-limiting organ toxicity. Through a systematic analysis of current literature, this review deciphers the dual regulat...

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Bibliographic Details
Main Authors: Zhonghao Liu, Dan Li, Xiongwen Yang, Xisha Chen, Chengxiao Fu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Chinese Medicine
Subjects:
Online Access:https://doi.org/10.1186/s13020-025-01170-6
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