Antidiabetic Potential of Hylocereus Polyrhizus and Hylocereus Megalanthus Fruit Peel: An In vitro Study

Background: Diabetes is a chronic metabolic condition affecting mainly carbohydrate metabolism. Dragon fruit is a commonly consumed fruit in Asia-pacific countries, with reported anti-diabetic potential. Objectives: The presents study explores the use of dragon fruit peel as an anti-diabetic supplem...

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Main Author: Fahad Saad. Alhodieb
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:https://journals.lww.com/10.4103/jpbs.jpbs_1289_24
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author Fahad Saad. Alhodieb
author_facet Fahad Saad. Alhodieb
author_sort Fahad Saad. Alhodieb
collection DOAJ
description Background: Diabetes is a chronic metabolic condition affecting mainly carbohydrate metabolism. Dragon fruit is a commonly consumed fruit in Asia-pacific countries, with reported anti-diabetic potential. Objectives: The presents study explores the use of dragon fruit peel as an anti-diabetic supplement. Materials And Method: Fruit peels from two varieties (Red and Yellow) were evaluated for their ability to absorb glucose, inhibit glucose diffusion, and inhibit starch digestion using in vitro models. Result: Both red and yellow dragon fruit peel powder samples decreased starch digestion significantly compared to wheat bran and inhibited glucose diffusion, as indicated by the glucose dialysis retardation index (GDRI) values. Conclusion: The findings of the study indicate that both red and yellow dragon fruit peel possesses significant antidiabetic potential.
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publisher Wolters Kluwer Medknow Publications
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series Journal of Pharmacy and Bioallied Sciences
spelling doaj-art-d0ff7101d6f3448b8d66bcf1fc8003742025-01-13T10:35:12ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-12-0116Suppl 4S3865S386710.4103/jpbs.jpbs_1289_24Antidiabetic Potential of Hylocereus Polyrhizus and Hylocereus Megalanthus Fruit Peel: An In vitro StudyFahad Saad. AlhodiebBackground: Diabetes is a chronic metabolic condition affecting mainly carbohydrate metabolism. Dragon fruit is a commonly consumed fruit in Asia-pacific countries, with reported anti-diabetic potential. Objectives: The presents study explores the use of dragon fruit peel as an anti-diabetic supplement. Materials And Method: Fruit peels from two varieties (Red and Yellow) were evaluated for their ability to absorb glucose, inhibit glucose diffusion, and inhibit starch digestion using in vitro models. Result: Both red and yellow dragon fruit peel powder samples decreased starch digestion significantly compared to wheat bran and inhibited glucose diffusion, as indicated by the glucose dialysis retardation index (GDRI) values. Conclusion: The findings of the study indicate that both red and yellow dragon fruit peel possesses significant antidiabetic potential.https://journals.lww.com/10.4103/jpbs.jpbs_1289_24α-amylaseantidiabeticdragon fruitglucose diffusionin vitro hypoglycemic
spellingShingle Fahad Saad. Alhodieb
Antidiabetic Potential of Hylocereus Polyrhizus and Hylocereus Megalanthus Fruit Peel: An In vitro Study
Journal of Pharmacy and Bioallied Sciences
α-amylase
antidiabetic
dragon fruit
glucose diffusion
in vitro hypoglycemic
title Antidiabetic Potential of Hylocereus Polyrhizus and Hylocereus Megalanthus Fruit Peel: An In vitro Study
title_full Antidiabetic Potential of Hylocereus Polyrhizus and Hylocereus Megalanthus Fruit Peel: An In vitro Study
title_fullStr Antidiabetic Potential of Hylocereus Polyrhizus and Hylocereus Megalanthus Fruit Peel: An In vitro Study
title_full_unstemmed Antidiabetic Potential of Hylocereus Polyrhizus and Hylocereus Megalanthus Fruit Peel: An In vitro Study
title_short Antidiabetic Potential of Hylocereus Polyrhizus and Hylocereus Megalanthus Fruit Peel: An In vitro Study
title_sort antidiabetic potential of hylocereus polyrhizus and hylocereus megalanthus fruit peel an in vitro study
topic α-amylase
antidiabetic
dragon fruit
glucose diffusion
in vitro hypoglycemic
url https://journals.lww.com/10.4103/jpbs.jpbs_1289_24
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