Antidiabetic Potential of Hylocereus Polyrhizus and Hylocereus Megalanthus Fruit Peel: An In vitro Study
Background: Diabetes is a chronic metabolic condition affecting mainly carbohydrate metabolism. Dragon fruit is a commonly consumed fruit in Asia-pacific countries, with reported anti-diabetic potential. Objectives: The presents study explores the use of dragon fruit peel as an anti-diabetic supplem...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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Series: | Journal of Pharmacy and Bioallied Sciences |
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Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_1289_24 |
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author | Fahad Saad. Alhodieb |
author_facet | Fahad Saad. Alhodieb |
author_sort | Fahad Saad. Alhodieb |
collection | DOAJ |
description | Background:
Diabetes is a chronic metabolic condition affecting mainly carbohydrate metabolism. Dragon fruit is a commonly consumed fruit in Asia-pacific countries, with reported anti-diabetic potential.
Objectives:
The presents study explores the use of dragon fruit peel as an anti-diabetic supplement.
Materials And Method:
Fruit peels from two varieties (Red and Yellow) were evaluated for their ability to absorb glucose, inhibit glucose diffusion, and inhibit starch digestion using in vitro models.
Result:
Both red and yellow dragon fruit peel powder samples decreased starch digestion significantly compared to wheat bran and inhibited glucose diffusion, as indicated by the glucose dialysis retardation index (GDRI) values.
Conclusion:
The findings of the study indicate that both red and yellow dragon fruit peel possesses significant antidiabetic potential. |
format | Article |
id | doaj-art-d0ff7101d6f3448b8d66bcf1fc800374 |
institution | Kabale University |
issn | 0976-4879 0975-7406 |
language | English |
publishDate | 2024-12-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Journal of Pharmacy and Bioallied Sciences |
spelling | doaj-art-d0ff7101d6f3448b8d66bcf1fc8003742025-01-13T10:35:12ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-12-0116Suppl 4S3865S386710.4103/jpbs.jpbs_1289_24Antidiabetic Potential of Hylocereus Polyrhizus and Hylocereus Megalanthus Fruit Peel: An In vitro StudyFahad Saad. AlhodiebBackground: Diabetes is a chronic metabolic condition affecting mainly carbohydrate metabolism. Dragon fruit is a commonly consumed fruit in Asia-pacific countries, with reported anti-diabetic potential. Objectives: The presents study explores the use of dragon fruit peel as an anti-diabetic supplement. Materials And Method: Fruit peels from two varieties (Red and Yellow) were evaluated for their ability to absorb glucose, inhibit glucose diffusion, and inhibit starch digestion using in vitro models. Result: Both red and yellow dragon fruit peel powder samples decreased starch digestion significantly compared to wheat bran and inhibited glucose diffusion, as indicated by the glucose dialysis retardation index (GDRI) values. Conclusion: The findings of the study indicate that both red and yellow dragon fruit peel possesses significant antidiabetic potential.https://journals.lww.com/10.4103/jpbs.jpbs_1289_24α-amylaseantidiabeticdragon fruitglucose diffusionin vitro hypoglycemic |
spellingShingle | Fahad Saad. Alhodieb Antidiabetic Potential of Hylocereus Polyrhizus and Hylocereus Megalanthus Fruit Peel: An In vitro Study Journal of Pharmacy and Bioallied Sciences α-amylase antidiabetic dragon fruit glucose diffusion in vitro hypoglycemic |
title | Antidiabetic Potential of Hylocereus Polyrhizus and Hylocereus Megalanthus Fruit Peel: An In vitro Study |
title_full | Antidiabetic Potential of Hylocereus Polyrhizus and Hylocereus Megalanthus Fruit Peel: An In vitro Study |
title_fullStr | Antidiabetic Potential of Hylocereus Polyrhizus and Hylocereus Megalanthus Fruit Peel: An In vitro Study |
title_full_unstemmed | Antidiabetic Potential of Hylocereus Polyrhizus and Hylocereus Megalanthus Fruit Peel: An In vitro Study |
title_short | Antidiabetic Potential of Hylocereus Polyrhizus and Hylocereus Megalanthus Fruit Peel: An In vitro Study |
title_sort | antidiabetic potential of hylocereus polyrhizus and hylocereus megalanthus fruit peel an in vitro study |
topic | α-amylase antidiabetic dragon fruit glucose diffusion in vitro hypoglycemic |
url | https://journals.lww.com/10.4103/jpbs.jpbs_1289_24 |
work_keys_str_mv | AT fahadsaadalhodieb antidiabeticpotentialofhylocereuspolyrhizusandhylocereusmegalanthusfruitpeelaninvitrostudy |