Anti-MDA5 antibody IgG1 subtype is associated with rapidly progressive interstitial lung disease in anti-MDA5-positive dermatomyositis

Anti-MDA5 antibody IgG1 subtype is associated with rapidly progressive interstitial lung disease in anti-MDA5-positive dermatomyositis

Abstract Background Rapidly progressive interstitial lung disease (RP-ILD) is a severe, often fatal complication in patients with anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis (MDA5+ DM). Early prediction of RP-ILD still remains challenging. We aimed to explore th...

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Bibliographic Details
Main Authors: Yun Wu, Yue Wang, Yulu Qiu, Chengying Lv, Yujing Zhu, Lei Wang, Lingxiao Xu, Hanxiao You, Fang Wang, Wenfeng Tan
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Anti-MDA5 antibody
IgG1
Rapidly progressive interstitial lung disease
Indirect immunofluorescence
Online Access:https://doi.org/10.1186/s13023-025-03921-y
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https://doi.org/10.1186/s13023-025-03921-y

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