Downregulation of aquaporins and PI3K/AKT and upregulation of PTEN expression induced by the flavone scutellarein in human colon cancer cell lines

Scutellarein has an anticancer potential, but the pathway of its action has not been elucidated. This study investigated scutellarein efficacy against human colorectal cancer (CRC) and explored the possible pathway of its action. MTT assay was employed to detect scutellarein effect on HT-29, SW-480,...

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Bibliographic Details
Main Authors: Noor Tarawneh, Lama Hamadneh, Walhan Alshaer, Abdel Qader Al Bawab, Yasser Bustanji, Shtaywy Abdalla
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Heliyon
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Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024154333
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