Advancements in herbal medicine-based nanozymes for biomedical applications
Abstract. Nanozymes are a distinct category of nanomaterials that exhibit catalytic properties resembling those of enzymes such as peroxidase (POD), superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx). Nanozymes derived from Chinese herbal medicines exhibit the catalytic fun...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer
2025-05-01
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| Series: | Chinese Medical Journal |
| Online Access: | http://journals.lww.com/10.1097/CM9.0000000000003584 |
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| _version_ | 1849313380524883968 |
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| author | Mei Yang Zhichao Deng Yuanyuan Zhu Chenxi Xu Chenguang Ding Yujie Zhang Mingxin Zhang Mingzhen Zhang Ting Gao |
| author_facet | Mei Yang Zhichao Deng Yuanyuan Zhu Chenxi Xu Chenguang Ding Yujie Zhang Mingxin Zhang Mingzhen Zhang Ting Gao |
| author_sort | Mei Yang |
| collection | DOAJ |
| description | Abstract. Nanozymes are a distinct category of nanomaterials that exhibit catalytic properties resembling those of enzymes such as peroxidase (POD), superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx). Nanozymes derived from Chinese herbal medicines exhibit the catalytic functions of their enzyme mimics, while retaining the specific medicinal properties of the herb (termed “herbzymes”). These nanozymes can be categorized into three main groups based on their method of synthesis: herb carbon dot nanozymes, polyphenol–metal nanozymes, and herb extract nanozymes. The reported catalytic activities of herbzymes include POD, SOD, CAT, and GPx. This review presents an overview of the catalytic activities and potential applications of nanozymes, introduces the novel concept of herbzymes, provides a comprehensive review of their classification and synthesis, and discusses recent advances in their biomedical applications. Furthermore, we also discuss the significance of research into herbzymes, including the primary challenges faced and future development directions. |
| format | Article |
| id | doaj-art-cfd6bf20a9ac4b569415b4e0ebaadbde |
| institution | Kabale University |
| issn | 0366-6999 2542-5641 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | Chinese Medical Journal |
| spelling | doaj-art-cfd6bf20a9ac4b569415b4e0ebaadbde2025-08-20T03:52:47ZengWolters KluwerChinese Medical Journal0366-69992542-56412025-05-0113891037104910.1097/CM9.0000000000003584202505050-00005Advancements in herbal medicine-based nanozymes for biomedical applicationsMei Yang0Zhichao Deng1Yuanyuan Zhu2Chenxi Xu3Chenguang Ding4Yujie Zhang5Mingxin Zhang6Mingzhen Zhang7Ting Gao1 Department of Organ Procurement and Allocation, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi 710061, China3 School of Basic Medical Sciences, Xi’an Jiaotong University, Xi’an, Shaanxi 710061, China3 School of Basic Medical Sciences, Xi’an Jiaotong University, Xi’an, Shaanxi 710061, China3 School of Basic Medical Sciences, Xi’an Jiaotong University, Xi’an, Shaanxi 710061, China1 Department of Organ Procurement and Allocation, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi 710061, China3 School of Basic Medical Sciences, Xi’an Jiaotong University, Xi’an, Shaanxi 710061, China5 Department of Gastroenterology, The First Affiliated Hospital of Xi’an Medical University, Xi’an, Shaanxi 710077, China3 School of Basic Medical Sciences, Xi’an Jiaotong University, Xi’an, Shaanxi 710061, ChinaAbstract. Nanozymes are a distinct category of nanomaterials that exhibit catalytic properties resembling those of enzymes such as peroxidase (POD), superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx). Nanozymes derived from Chinese herbal medicines exhibit the catalytic functions of their enzyme mimics, while retaining the specific medicinal properties of the herb (termed “herbzymes”). These nanozymes can be categorized into three main groups based on their method of synthesis: herb carbon dot nanozymes, polyphenol–metal nanozymes, and herb extract nanozymes. The reported catalytic activities of herbzymes include POD, SOD, CAT, and GPx. This review presents an overview of the catalytic activities and potential applications of nanozymes, introduces the novel concept of herbzymes, provides a comprehensive review of their classification and synthesis, and discusses recent advances in their biomedical applications. Furthermore, we also discuss the significance of research into herbzymes, including the primary challenges faced and future development directions.http://journals.lww.com/10.1097/CM9.0000000000003584 |
| spellingShingle | Mei Yang Zhichao Deng Yuanyuan Zhu Chenxi Xu Chenguang Ding Yujie Zhang Mingxin Zhang Mingzhen Zhang Ting Gao Advancements in herbal medicine-based nanozymes for biomedical applications Chinese Medical Journal |
| title | Advancements in herbal medicine-based nanozymes for biomedical applications |
| title_full | Advancements in herbal medicine-based nanozymes for biomedical applications |
| title_fullStr | Advancements in herbal medicine-based nanozymes for biomedical applications |
| title_full_unstemmed | Advancements in herbal medicine-based nanozymes for biomedical applications |
| title_short | Advancements in herbal medicine-based nanozymes for biomedical applications |
| title_sort | advancements in herbal medicine based nanozymes for biomedical applications |
| url | http://journals.lww.com/10.1097/CM9.0000000000003584 |
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