Spatial transcriptomics reveals strong association between SFRP4 and extracellular matrix remodeling in prostate cancer

Spatial transcriptomics reveals strong association between SFRP4 and extracellular matrix remodeling in prostate cancer

Abstract Prostate tumor heterogeneity is a major obstacle when studying the biological mechanisms of molecular markers. Increased gene expression levels of secreted frizzled-related protein 4 (SFRP4) is a biomarker in aggressive prostate cancer. To understand how SFRP4 relates to prostate cancer we...

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Main Authors: Maria K. Andersen, Sebastian Krossa, Elise Midtbust, Christine A. Pedersen, Maximilian Wess, Therese S. Høiem, Trond Viset, Øystein Størkersen, Ingunn Nervik, Elise Sandsmark, Helena Bertilsson, Guro F. Giskeødegård, Morten B. Rye, May-Britt Tessem
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-07161-x
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https://doi.org/10.1038/s42003-024-07161-x

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