Ferroptosis induces nucleolar stress as revealed by live-cell imaging using thioflavin T

Nucleolar stress induced by stressors like hypoxia, UV irradiation, and heat shock downregulates ribosomal RNA transcription, thereby impairing protein synthesis capacity and potentially contributing to cell senescence and various human diseases such as neurodegenerative disorders and cancer. Live-c...

Full description

Saved in:
Bibliographic Details
Main Authors: Yoko Hirata, Hiroshi Takemori, Kyoji Furuta, Yuji O. Kamatari, Makoto Sawada
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Current Research in Pharmacology and Drug Discovery
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590257124000233
Tags: Add Tag
No Tags, Be the first to tag this record!