Interaction of AURKA with TRIM28 revives dormant LSCC cells via Akt signaling pathway to promote LSCC metastasis

Interaction of AURKA with TRIM28 revives dormant LSCC cells via Akt signaling pathway to promote LSCC metastasis

Abstract Background Specific molecular mechanisms by which AURKA promoted LSCC metastasis were still unknown. Methods Bioinformatic analysis was performed the relationship between TRIM28 and LSCC. Immunohistochemistry, Co-IP assay, Rt-PCR and Western Blot were used to examine the expression of relat...

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Bibliographic Details
Main Authors: Liyun Yang, Liang Geng, Xinxin Zhang, Jing Lu, Hao Zhang, Geping Wu, Shuixian Huang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Cancer Cell International
Subjects:
TRIM28
AURKA
LSCC metastasis
Bioinformatic analysis
Akt signaling pathway
Online Access:https://doi.org/10.1186/s12935-024-03620-x
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