Extensive DNA end processing by exo1 and sgs1 inhibits break-induced replication.

Extensive DNA end processing by exo1 and sgs1 inhibits break-induced replication.

Homology-dependent repair of DNA double-strand breaks (DSBs) by gene conversion involves short tracts of DNA synthesis and limited loss of heterozygosity (LOH). For DSBs that present only one end, repair occurs by invasion into a homologous sequence followed by replication to the end of the chromoso...

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Bibliographic Details
Main Authors: Vanessa A Marrero, Lorraine S Symington
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1001007&type=printable
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