Redox Mechanisms Driving Skin Fibroblast-to-Myofibroblast Differentiation

Redox Mechanisms Driving Skin Fibroblast-to-Myofibroblast Differentiation

Transforming Growth Factor-Beta 1 (TGF-β1) plays a pivotal role in the differentiation of fibroblasts into myofibroblasts, which is a critical process in tissue repair, fibrosis, and wound healing. Upon exposure to TGF-β1, fibroblasts acquire a contractile phenotype and secrete collagen and extracel...

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Bibliographic Details
Main Authors:	Marzieh Aminzadehanboohi, Manousos Makridakis, Delphine Rasti, Yves Cambet, Karl-Heinz Krause, Antonia Vlahou, Vincent Jaquet
Format:	Article
Language:	English
Published:	MDPI AG 2025-04-01
Series:	Antioxidants
Subjects:	proteomics thiol oxidation redox signalling fibroblasts myofibroblasts transforming growth factor β1
Online Access:	https://www.mdpi.com/2076-3921/14/4/486
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