Redox Mechanisms Driving Skin Fibroblast-to-Myofibroblast Differentiation

Redox Mechanisms Driving Skin Fibroblast-to-Myofibroblast Differentiation

Transforming Growth Factor-Beta 1 (TGF-β1) plays a pivotal role in the differentiation of fibroblasts into myofibroblasts, which is a critical process in tissue repair, fibrosis, and wound healing. Upon exposure to TGF-β1, fibroblasts acquire a contractile phenotype and secrete collagen and extracel...

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Bibliographic Details
Main Authors: Marzieh Aminzadehanboohi, Manousos Makridakis, Delphine Rasti, Yves Cambet, Karl-Heinz Krause, Antonia Vlahou, Vincent Jaquet
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Antioxidants
Subjects:
proteomics
thiol oxidation
redox signalling
fibroblasts
myofibroblasts
transforming growth factor β1
Online Access:https://www.mdpi.com/2076-3921/14/4/486
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