Routine Genetic Testing of Germline Breast Cancer Susceptibility ─ Challenges and Opportunities

Information on germline BRCA (g*BRCA*) 1/2 pathogenic or likely pathogenic mutations has predictive value for response to platinating agents and poly(ADP-ribose) polymerase inhibitors (PARPi) and survival outcomes of breast cancer (BC) patients. In the OlympiA trial, the benefits of adjuvant olapari...

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Bibliographic Details
Main Authors: Cornelia Leo, Kathrin Schwedler, Rosaria Condorelli, Nicole Bürki, Jens Huober, Khalil Zaman, Christian Kurzeder, Marcus Vetter
Format: Article
Language:English
Published: THE HEALTHBOOK COMPANY LTD. 2023-10-01
Series:healthbook TIMES. Oncology Hematology
Online Access:https://doi.org/10.36000/HBT.OH.2023.17.117
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