Sendotypes predict worsening renal function in chronic kidney disease patients

Sendotypes predict worsening renal function in chronic kidney disease patients

Abstract Background Senescence associated secretory phenotype (SASP) contributes to age‐related pathology, however the role of SASP in Chronic Kidney Disease (CKD) is unclear. Here, we employ a variety of omic techniques to show that senescence signatures can separate CKD patients into distinct sene...

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Main Authors: Thomas McLarnon, Steven Watterson, Sean McCallion, Eamonn Cooper, Andrew R. English, Ying Kuan, David S. Gibson, Elaine K. Murray, Frank McCarroll, Shu‐Dong Zhang, Anthony J. Bjourson, Taranjit Singh Rai
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Clinical and Translational Medicine
Subjects:
biomarker
CKD
machine learning
sendotype
senescence
Online Access:https://doi.org/10.1002/ctm2.70279
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https://doi.org/10.1002/ctm2.70279

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