Choline alleviates cognitive impairment in sleep-deprived young mice via reducing neuroinflammation and altering phospholipidomic profile

Choline alleviates cognitive impairment in sleep-deprived young mice via reducing neuroinflammation and altering phospholipidomic profile

Cognitive impairment resulting from insufficient sleep poses a significant public health concern, particularly in children. The effects and mechanisms of choline on cognitive impairment caused by sleep deprivation are unknown. Chronic sleep deprivation is induced in young mice in this study, followe...

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Bibliographic Details
Main Authors: Si-Yu Huang, Zhi-Jun Yang, Jin Cheng, Hang-Yu Li, Si Chen, Zi-Hui Huang, Jie-Dong Chen, Ruo-Gu Xiong, Meng-Tao Yang, Chen Wang, Meng-Chu Li, Shuang Song, Wen-Ge Huang, Dong-Liang Wang, Hua-Bin Li, Qiu-Ye Lan
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Redox Biology
Subjects:
Choline
Sleep deprivation
Cognitive impairment
Neuroinflammation
Magnetic resonance imaging
Phospholipidomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725000916
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