A multi‐scale approach reveals that NF‐κB cRel enforces a B‐cell decision to divide

A multi‐scale approach reveals that NF‐κB cRel enforces a B‐cell decision to divide

Abstract Understanding the functions of multi‐cellular organs in terms of the molecular networks within each cell is an important step in the quest to predict phenotype from genotype. B‐lymphocyte population dynamics, which are predictive of immune response and vaccine effectiveness, are determined...

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Bibliographic Details
Main Authors: Maxim N Shokhirev, Jonathan Almaden, Jeremy Davis‐Turak, Harry A Birnbaum, Theresa M Russell, Jesse A D Vargas, Alexander Hoffmann
Format: Article
Language:English
Published: Springer Nature 2015-02-01
Series:Molecular Systems Biology
Subjects:
apoptosis
B‐lymphocyte
cell cycle
cell fate decision
NF‐κB cRel
Online Access:https://doi.org/10.15252/msb.20145554
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https://doi.org/10.15252/msb.20145554

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