Lithium-doped calcium silicate cement regulates the immune microenvironment and promotes M2 macrophage polarization for enhancing bone regeneration

Lithium-doped calcium silicate cement regulates the immune microenvironment and promotes M2 macrophage polarization for enhancing bone regeneration

Abstract Bone defects present a significant challenge in orthopedics and trauma surgery, necessitating innovative approaches to stimulate effective bone regeneration. This study investigated the potential of lithium-doped calcium silicate (LiCS) cement to enhance bone regeneration and modulate the i...

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Bibliographic Details
Main Authors: Yen-Hong Lin, Cheng-Yu Chen, Kun-Hao Chen, Ting-You Kuo, Tsung-Li Lin, Ming-You Shie
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Biological Engineering
Subjects:
Lithium
Calcium silicate
Bone regeneration
Immune modulation
Macrophage polarization
Osteogenesis
Online Access:https://doi.org/10.1186/s13036-024-00467-8
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https://doi.org/10.1186/s13036-024-00467-8

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