Therapeutic drug monitoring and neutralizing anti-drug antibody detection to optimize TNF-alpha inhibitor treatment for uveitis

Therapeutic drug monitoring and neutralizing anti-drug antibody detection to optimize TNF-alpha inhibitor treatment for uveitis

BackgroundAdalimumab taken every other week is an effective treatment in patients with chronic refractory uveitis. Patients who have a suboptimal response to this treatment may suffer from recurrent inflammation and vision loss. Here, we investigated the use of therapeutic drug monitoring and neutra...

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Bibliographic Details
Main Authors: Howard C. Chen, Jenny Shunyakova, Amit K. Reddy, Srujay Pandiri, Lynn Hassman
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Ophthalmology
Subjects:
therapeutic drug monitoring
anti-drug antibodies
TNF-alpha inhibitors
uveitis
adalimumab
infliximab
Online Access:https://www.frontiersin.org/articles/10.3389/fopht.2025.1432935/full
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