Low-level laser therapy: an efficient supplement to treatments of vulvar Lichen sclerosus to improve quality of life

Background Lichen sclerosus (LS) is a chronic, inflammatory disease of the genital and extra genital skin, causing pruritus, soreness, pain and dyspareunia. The aim of this study was to investigate whether Low Level Laser Therapy (LLLT) can improve the quality of life in women with Lichen sclerosus...

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Main Authors: Pia Kirstine Berthelsen, Sidsel Eb Ipsen, Mohammed R. Khalil
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Journal of Obstetrics and Gynaecology
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Online Access:https://www.tandfonline.com/doi/10.1080/01443615.2024.2349965
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author Pia Kirstine Berthelsen
Sidsel Eb Ipsen
Mohammed R. Khalil
author_facet Pia Kirstine Berthelsen
Sidsel Eb Ipsen
Mohammed R. Khalil
author_sort Pia Kirstine Berthelsen
collection DOAJ
description Background Lichen sclerosus (LS) is a chronic, inflammatory disease of the genital and extra genital skin, causing pruritus, soreness, pain and dyspareunia. The aim of this study was to investigate whether Low Level Laser Therapy (LLLT) can improve the quality of life in women with Lichen sclerosus (LS) and insufficient topical treatment.Methods In a descriptive prospective observational study conducted between 02.01.2016 and 08.01.2018, we included 100 women with LS with insufficient topical treatment because of poor response of symptoms. All participants received ten LLLT treatments (808 nm and 500 mW) over a period of 8 weeks. The first four treatments were planned as two treatments per week. The remaining six treatments were planned as once a week. A Danish health-related quality of life tool (HRQoL test) monitored the effect.Results A total of 94 patients completed the study, median age of 62 [InterQuartile Range 53–69]. There was a statistically significant improvement in seven of the eight domains of the HRQoL test after ten LLLT. We found the results of DoloTest to be statistically significant in all of the groups except for smoking (p < 0.094).Conclusions LLLT treatment can improve the quality of life in women with LS.
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publishDate 2024-12-01
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series Journal of Obstetrics and Gynaecology
spelling doaj-art-cdb920c58b1741699f811615edc813df2025-01-09T12:13:17ZengTaylor & Francis GroupJournal of Obstetrics and Gynaecology0144-36151364-68932024-12-0144110.1080/01443615.2024.2349965Low-level laser therapy: an efficient supplement to treatments of vulvar Lichen sclerosus to improve quality of lifePia Kirstine Berthelsen0Sidsel Eb Ipsen1Mohammed R. Khalil2Department of Obstetrics and Gynecology, University Hospital of Southern Denmark, Lillebaelt Hospital, Kolding, DenmarkDepartment of Obstetrics and Gynecology, University Hospital of Southern Denmark, Sydvest Jysk Hospital, Esbjerg, DenmarkDepartment of Obstetrics and Gynecology, University Hospital of Southern Denmark, Lillebaelt Hospital, Kolding, DenmarkBackground Lichen sclerosus (LS) is a chronic, inflammatory disease of the genital and extra genital skin, causing pruritus, soreness, pain and dyspareunia. The aim of this study was to investigate whether Low Level Laser Therapy (LLLT) can improve the quality of life in women with Lichen sclerosus (LS) and insufficient topical treatment.Methods In a descriptive prospective observational study conducted between 02.01.2016 and 08.01.2018, we included 100 women with LS with insufficient topical treatment because of poor response of symptoms. All participants received ten LLLT treatments (808 nm and 500 mW) over a period of 8 weeks. The first four treatments were planned as two treatments per week. The remaining six treatments were planned as once a week. A Danish health-related quality of life tool (HRQoL test) monitored the effect.Results A total of 94 patients completed the study, median age of 62 [InterQuartile Range 53–69]. There was a statistically significant improvement in seven of the eight domains of the HRQoL test after ten LLLT. We found the results of DoloTest to be statistically significant in all of the groups except for smoking (p < 0.094).Conclusions LLLT treatment can improve the quality of life in women with LS.https://www.tandfonline.com/doi/10.1080/01443615.2024.2349965Low-level laser therapyphotobiomodulationvulva Lichen sclerosusquality of life
spellingShingle Pia Kirstine Berthelsen
Sidsel Eb Ipsen
Mohammed R. Khalil
Low-level laser therapy: an efficient supplement to treatments of vulvar Lichen sclerosus to improve quality of life
Journal of Obstetrics and Gynaecology
Low-level laser therapy
photobiomodulation
vulva Lichen sclerosus
quality of life
title Low-level laser therapy: an efficient supplement to treatments of vulvar Lichen sclerosus to improve quality of life
title_full Low-level laser therapy: an efficient supplement to treatments of vulvar Lichen sclerosus to improve quality of life
title_fullStr Low-level laser therapy: an efficient supplement to treatments of vulvar Lichen sclerosus to improve quality of life
title_full_unstemmed Low-level laser therapy: an efficient supplement to treatments of vulvar Lichen sclerosus to improve quality of life
title_short Low-level laser therapy: an efficient supplement to treatments of vulvar Lichen sclerosus to improve quality of life
title_sort low level laser therapy an efficient supplement to treatments of vulvar lichen sclerosus to improve quality of life
topic Low-level laser therapy
photobiomodulation
vulva Lichen sclerosus
quality of life
url https://www.tandfonline.com/doi/10.1080/01443615.2024.2349965
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AT sidselebipsen lowlevellasertherapyanefficientsupplementtotreatmentsofvulvarlichensclerosustoimprovequalityoflife
AT mohammedrkhalil lowlevellasertherapyanefficientsupplementtotreatmentsofvulvarlichensclerosustoimprovequalityoflife