Effect of Robusta Coffee Extract on Histopathological in Mice Testes Induced with Monosodium Glutamat
Monosodium glutamate (MSG) is a sodium salt from glutamic acid which is currently very popular to be used as a food flavoring ingredient to stimulate appetite. Exessive consumption of MSG can disrupt the balance of antioxidants and ROS, and cause the negative effects of oxidative stress on testes. C...
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| Format: | Article |
| Language: | English |
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Universitas Airlangga, Faculty of Veterinary Medicine
2021-10-01
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| Series: | Jurnal Medik Veteriner |
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| Online Access: | https://e-journal.unair.ac.id/JMV/article/view/21809 |
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| author | Trima Weliyani Iwan Sahrial Hamid Sri Hidanah Ragil Angga Prastiya Prima Ayu Wibawati |
| author_facet | Trima Weliyani Iwan Sahrial Hamid Sri Hidanah Ragil Angga Prastiya Prima Ayu Wibawati |
| author_sort | Trima Weliyani |
| collection | DOAJ |
| description | Monosodium glutamate (MSG) is a sodium salt from glutamic acid which is currently very popular to be used as a food flavoring ingredient to stimulate appetite. Exessive consumption of MSG can disrupt the balance of antioxidants and ROS, and cause the negative effects of oxidative stress on testes. Coffee has high chlorogenic acid, function for antioxidants and reduce the negative effect on cell damage in the testes. This study aims to analyze the effect of robusta coffee extract on histological of mice testes induced with MSG. This study was completely randomized design (CRD), using 20 male mice for 5 treatment groups: K+ (MSG 0.12 mg and Vitamin C 6 mg), K- (MSG 0.12 mg and CMC Na 0.1 ml), P1 (MSG 0.12 mg and RCE 0.1 mg), P2 (MSG 0.12 mg and RCE 0.2 mg), and P3 (MSG 0.12 mg and RCE 0.4 mg) orally for 42 days. Histophatological scores were analyzed with Saphiro-Wilk Test and Anova. There is no effect of increasing testicular weight. 0,12 mg MSG can cause a decrease in the number of spermatogonia and spermatocytes. 0,2 mg robusta coffee extract can maintain the number of spermatogonia and spermatocytes. |
| format | Article |
| id | doaj-art-cda6e1825e7f431baed3f47f9b034607 |
| institution | Kabale University |
| issn | 2615-7497 2581-012X |
| language | English |
| publishDate | 2021-10-01 |
| publisher | Universitas Airlangga, Faculty of Veterinary Medicine |
| record_format | Article |
| series | Jurnal Medik Veteriner |
| spelling | doaj-art-cda6e1825e7f431baed3f47f9b0346072025-01-02T20:28:16ZengUniversitas Airlangga, Faculty of Veterinary MedicineJurnal Medik Veteriner2615-74972581-012X2021-10-014224324810.20473/jmv.vol4.iss2.2021.243-24817849Effect of Robusta Coffee Extract on Histopathological in Mice Testes Induced with Monosodium GlutamatTrima Weliyani0Iwan Sahrial Hamid1Sri Hidanah2Ragil Angga Prastiya3Prima Ayu Wibawati4Mahasiswa, Fakultas Kedokteran Hewan, Universitas AirlanggaDepartemen Ilmu Kedokteran Dasar Veteriner, Fakultas Kedokteran Hewan, Universitas AirlanggaDepartemen Peternakan, Fakultas Kedokteran Hewan, Universitas AirlanggaDepartemen Reproduksi Veteriner, Fakultas Kedokteran Hewan, Universitas AirlanggaDepartemen Kesehatan Masyarakat Veteriner, Fakultas Kedokteran Hewan, Universitas AirlanggaMonosodium glutamate (MSG) is a sodium salt from glutamic acid which is currently very popular to be used as a food flavoring ingredient to stimulate appetite. Exessive consumption of MSG can disrupt the balance of antioxidants and ROS, and cause the negative effects of oxidative stress on testes. Coffee has high chlorogenic acid, function for antioxidants and reduce the negative effect on cell damage in the testes. This study aims to analyze the effect of robusta coffee extract on histological of mice testes induced with MSG. This study was completely randomized design (CRD), using 20 male mice for 5 treatment groups: K+ (MSG 0.12 mg and Vitamin C 6 mg), K- (MSG 0.12 mg and CMC Na 0.1 ml), P1 (MSG 0.12 mg and RCE 0.1 mg), P2 (MSG 0.12 mg and RCE 0.2 mg), and P3 (MSG 0.12 mg and RCE 0.4 mg) orally for 42 days. Histophatological scores were analyzed with Saphiro-Wilk Test and Anova. There is no effect of increasing testicular weight. 0,12 mg MSG can cause a decrease in the number of spermatogonia and spermatocytes. 0,2 mg robusta coffee extract can maintain the number of spermatogonia and spermatocytes.https://e-journal.unair.ac.id/JMV/article/view/21809monosodium glutamatrobusta coffeetestes |
| spellingShingle | Trima Weliyani Iwan Sahrial Hamid Sri Hidanah Ragil Angga Prastiya Prima Ayu Wibawati Effect of Robusta Coffee Extract on Histopathological in Mice Testes Induced with Monosodium Glutamat Jurnal Medik Veteriner monosodium glutamat robusta coffee testes |
| title | Effect of Robusta Coffee Extract on Histopathological in Mice Testes Induced with Monosodium Glutamat |
| title_full | Effect of Robusta Coffee Extract on Histopathological in Mice Testes Induced with Monosodium Glutamat |
| title_fullStr | Effect of Robusta Coffee Extract on Histopathological in Mice Testes Induced with Monosodium Glutamat |
| title_full_unstemmed | Effect of Robusta Coffee Extract on Histopathological in Mice Testes Induced with Monosodium Glutamat |
| title_short | Effect of Robusta Coffee Extract on Histopathological in Mice Testes Induced with Monosodium Glutamat |
| title_sort | effect of robusta coffee extract on histopathological in mice testes induced with monosodium glutamat |
| topic | monosodium glutamat robusta coffee testes |
| url | https://e-journal.unair.ac.id/JMV/article/view/21809 |
| work_keys_str_mv | AT trimaweliyani effectofrobustacoffeeextractonhistopathologicalinmicetestesinducedwithmonosodiumglutamat AT iwansahrialhamid effectofrobustacoffeeextractonhistopathologicalinmicetestesinducedwithmonosodiumglutamat AT srihidanah effectofrobustacoffeeextractonhistopathologicalinmicetestesinducedwithmonosodiumglutamat AT ragilanggaprastiya effectofrobustacoffeeextractonhistopathologicalinmicetestesinducedwithmonosodiumglutamat AT primaayuwibawati effectofrobustacoffeeextractonhistopathologicalinmicetestesinducedwithmonosodiumglutamat |