Synergistic and off-target effects of bacteriocins in a simplified human intestinal microbiome: implications for Clostridioides difficile infection control

Synergistic and off-target effects of bacteriocins in a simplified human intestinal microbiome: implications for Clostridioides difficile infection control

Clostridioides difficile is a major cause of nosocomial diarrhea. As current antibiotic treatment failures and recurrence of infections are highly frequent, alternative strategies are needed for the treatment of this disease. This study explores the use of bacteriocins, specifically lacticin 3147 an...

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Bibliographic Details
Main Authors: Natalia S. Ríos Colombo, R. Paul Ross, Colin Hill
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
C. difficile
bacteriocin
microbiome
lantibiotic
pediocin PA-1
lacticin 3147
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2451081
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