Mechanical tension-induced Dalrd3 elevation enhances osteogenic differentiation of bone suture stem cells by upregulating Id3 translation

Mechanical tension-induced Dalrd3 elevation enhances osteogenic differentiation of bone suture stem cells by upregulating Id3 translation

Abstract Background Craniomaxillofacial sutures play a critical role in craniomaxillofacial development through continuous bone reconstruction and regeneration, processes modulated by mechanical tension. Bone suture stem cells (SuSCs) are central to these functions. Distraction osteogenesis, which p...

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Bibliographic Details
Main Authors: Jie Chen, Yiwei Zhao, Chongmai Zeng, Guoli Tian, Zhicai Feng, Yang Cao
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Stem Cell Research & Therapy
Subjects:
Bone suture stem cells
Mechanical tension
Dalrd3
Osteogenesis
TRNA m3 C modification
Online Access:https://doi.org/10.1186/s13287-025-04380-9
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https://doi.org/10.1186/s13287-025-04380-9

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