Protocol to detect spontaneous termination of yeast RNAPII transcription in vitro

Summary: We present a protocol for the in vitro detection of spontaneous termination of yeast RNA polymerase II (RNAPII) transcription using bead-immobilized elongation complexes (ECs). We describe the steps for EC assembly, ligation to a long transcription template, and the in vitro elongation and...

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Bibliographic Details
Main Authors: Zhong Han, Jesper Q. Svejstrup
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:STAR Protocols
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666166724005343
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