Pharmacokinetic Adaptations in Pregnancy: Implications for Optimizing Antiretroviral Therapy in HIV-Positive Women

Pharmacokinetic Adaptations in Pregnancy: Implications for Optimizing Antiretroviral Therapy in HIV-Positive Women

Pregnancy introduces significant physiological changes that alter the pharmacokinetics (PK) of antiretroviral therapy (ART), impacting its safety and efficacy in HIV-positive women. Optimizing ART during pregnancy is critical to maintaining maternal virological suppression and preventing mother-to-c...

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Bibliographic Details
Main Authors: Natalia Briceño-Patiño, María Camila Prieto, Paula Manrique, Carlos-Alberto Calderon-Ospina, Leonardo Gómez
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Pharmaceutics
Subjects:
pharmacokinetics
pregnancy
antiretroviral therapy
HIV seropositivity
infectious disease transmission
vertical
Online Access:https://www.mdpi.com/1999-4923/17/7/913
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