The role of AIM2 in inflammation and tumors

Absent in melanoma 2 (AIM2) serves as an intracellular nucleic acid sensor that predominantly detects double-stranded DNA (dsDNA) within the cells. This detection initiates the assembly of inflammasome and activates the inflammasome signaling cascade, resulting in the production of inflammatory medi...

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Bibliographic Details
Main Authors: Dalang Yu, Siping Zheng, Lina Sui, Yuling Xi, Tiansheng He, Zhiping Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1466440/full
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