Mechanisms of Cefiderocol Resistance in Carbapenemase-Producing Enterobacterales: Insights from Comparative Genomics

Mechanisms of Cefiderocol Resistance in Carbapenemase-Producing Enterobacterales: Insights from Comparative Genomics

<b>Background/Objectives</b>: Cefiderocol is a novel siderophore cephalosporin with potent in vitro activity against a broad spectrum of Gram-negative bacteria, including carbapenemase-producing Enterobacterales (CPE). However, the recent emergence of resistance in clinical settings rais...

Full description

Saved in:
Bibliographic Details
Main Authors: Alexander Tristancho-Baró, Ana Isabel López-Calleja, Ana Milagro, Mónica Ariza, Víctor Viñeta, Blanca Fortuño, Concepción López, Miriam Latorre-Millán, Laura Clusa, David Badenas-Alzugaray, Rosa Martínez, Carmen Torres, Antonio Rezusta
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Antibiotics
Subjects:
carbapenem-resistant enterobacterales
comparative genomics
antimicrobial resistance
whole-genome sequencing
Online Access:https://www.mdpi.com/2079-6382/14/7/703
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2079-6382/14/7/703

Similar Items