Nrf2 Deficiency Brings About Increased Sensitive to IR and 7,12-dimethylbenz(a)anthracene and Leukemia Predisposition

Purpose Nuclear factor erythroid 2-related factor 2 (Nrf2) is a crucial cytoprotective protein that shields cells from electrophilic and oxidative stress. Mice lacking Nrf2 exhibit heightened susceptibility to myelosuppression due to impaired hematopoietic reconstitution. In this study, we examined...

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Bibliographic Details
Main Authors: Mingxin Dong, Ping Yang, Xinyu Zhang, Shasha Nie, Xiaohui Sun
Format: Article
Language:English
Published: SAGE Publishing 2025-05-01
Series:Dose-Response
Online Access:https://doi.org/10.1177/15593258251341593
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