Antimicrobial activity and synergistic effect of phage-encoded antimicrobial peptides with colistin and outer membrane permeabilizing agents against Acinetobacter baumannii

Antimicrobial activity and synergistic effect of phage-encoded antimicrobial peptides with colistin and outer membrane permeabilizing agents against Acinetobacter baumannii

Background Acinetobacter baumannii poses a significant public health threat. Phage-encoded antimicrobial peptides (AMPs) have emerged as promising candidates in the battle against antibiotic-resistant A. baumannii. Methods Antimicrobial peptides from the endolysin of A. baumannii bacteriophage were...

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Bibliographic Details
Main Authors: Punnaphat Rothong, Udomluk Leungtongkam, Supat Khongfak, Chanatinat Homkaew, Sirorat Samathi, Sarunporn Tandhavanant, Jatuporn Ngoenkam, Apichat Vitta, Aunchalee Thanwisai, Sutthirat Sitthisak
Format: Article
Language:English
Published: PeerJ Inc. 2024-12-01
Series:PeerJ
Subjects:
Bacteriophage
Acinetobacter baumannii
Phage-encoded peptide
Antimicrobial activity
Biofilm
G. mellonella assay
Online Access:https://peerj.com/articles/18722.pdf
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