ANTIBACTERIAL ACTIVITY OF XANTHONE FROM ETHYL ACETATE EXTRACT OF THE STEAM BARK OF Garcinia picrorrhiza Miq
A compound was isolated from the ethyl acetate extract of stem bark Garcinia picrorrhiza. The extraction was conducted by maseration. Separation and purification were done by chromatography method. The structure of compound was established using UV, IR, and 1H NMR spectroscopy. The antibacteria acti...
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| Format: | Article |
| Language: | English |
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Universitas Sebelas Maret
2017-08-01
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| Series: | Alchemy |
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| Online Access: | https://jurnal.uns.ac.id/alchemy/article/view/4346 |
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| author | Muharni Muharni Elfita Elfita Emil Pertiwi |
| author_facet | Muharni Muharni Elfita Elfita Emil Pertiwi |
| author_sort | Muharni Muharni |
| collection | DOAJ |
| description | A compound was isolated from the ethyl acetate extract of stem bark Garcinia picrorrhiza. The extraction was conducted by maseration. Separation and purification were done by chromatography method. The structure of compound was established using UV, IR, and 1H NMR spectroscopy. The antibacteria activity of the isolated compound was tested by paper disk difusion method and minimum inhibitory concentration (MIC) value was determined by using well difusion method examined against bacteria Escherechia coli, Salmonella typhi, Bacillus subtilis and Staphyloccocus aureus. The isolated compound was a yellow solids (43.8 mg) with melting point 171 – 172 oC. Based on spectroscopy data compared with data from the literature, the isolated compound is a known compound of oxygenated xanthone group with structure 1,4,5-trihydroxy-2-(3methylbut-2-enyl)xanthone. The compound exhibited an antibacterial activity against Bacillus subtilis only with MIC of 62.5 µg/mL. |
| format | Article |
| id | doaj-art-ca418066f2994156a645c6b2cdb880b8 |
| institution | Kabale University |
| issn | 1412-4092 2443-4183 |
| language | English |
| publishDate | 2017-08-01 |
| publisher | Universitas Sebelas Maret |
| record_format | Article |
| series | Alchemy |
| spelling | doaj-art-ca418066f2994156a645c6b2cdb880b82025-01-02T11:16:09ZengUniversitas Sebelas MaretAlchemy1412-40922443-41832017-08-0113225026110.20961/alchemy.0.0.4346.%p11102ANTIBACTERIAL ACTIVITY OF XANTHONE FROM ETHYL ACETATE EXTRACT OF THE STEAM BARK OF Garcinia picrorrhiza MiqMuharni Muharni0Elfita Elfita1Emil Pertiwi2Department of Chemistry, Faculty of Mathematics and Natural Sciences , Sriwijaya University, Jl. Raya Palembang Prabumulih Km 32, Indralaya, Ogan Ilir, South Sumatera, 30662,IndonesiaDepartment of Chemistry, Faculty of Mathematics and Natural Sciences , Sriwijaya University, Jl. Raya Palembang Prabumulih Km 32, Indralaya, Ogan Ilir, South Sumatera, 30662,IndonesiaDepartment of Chemistry, Faculty of Mathematics and Natural Sciences , Sriwijaya University, Jl. Raya Palembang Prabumulih Km 32, Indralaya, Ogan Ilir, South Sumatera, 30662,IndonesiaA compound was isolated from the ethyl acetate extract of stem bark Garcinia picrorrhiza. The extraction was conducted by maseration. Separation and purification were done by chromatography method. The structure of compound was established using UV, IR, and 1H NMR spectroscopy. The antibacteria activity of the isolated compound was tested by paper disk difusion method and minimum inhibitory concentration (MIC) value was determined by using well difusion method examined against bacteria Escherechia coli, Salmonella typhi, Bacillus subtilis and Staphyloccocus aureus. The isolated compound was a yellow solids (43.8 mg) with melting point 171 – 172 oC. Based on spectroscopy data compared with data from the literature, the isolated compound is a known compound of oxygenated xanthone group with structure 1,4,5-trihydroxy-2-(3methylbut-2-enyl)xanthone. The compound exhibited an antibacterial activity against Bacillus subtilis only with MIC of 62.5 µg/mL.https://jurnal.uns.ac.id/alchemy/article/view/4346antibacterialGarcinia picrorrhiza Miqxanthone |
| spellingShingle | Muharni Muharni Elfita Elfita Emil Pertiwi ANTIBACTERIAL ACTIVITY OF XANTHONE FROM ETHYL ACETATE EXTRACT OF THE STEAM BARK OF Garcinia picrorrhiza Miq Alchemy antibacterial Garcinia picrorrhiza Miq xanthone |
| title | ANTIBACTERIAL ACTIVITY OF XANTHONE FROM ETHYL ACETATE EXTRACT OF THE STEAM BARK OF Garcinia picrorrhiza Miq |
| title_full | ANTIBACTERIAL ACTIVITY OF XANTHONE FROM ETHYL ACETATE EXTRACT OF THE STEAM BARK OF Garcinia picrorrhiza Miq |
| title_fullStr | ANTIBACTERIAL ACTIVITY OF XANTHONE FROM ETHYL ACETATE EXTRACT OF THE STEAM BARK OF Garcinia picrorrhiza Miq |
| title_full_unstemmed | ANTIBACTERIAL ACTIVITY OF XANTHONE FROM ETHYL ACETATE EXTRACT OF THE STEAM BARK OF Garcinia picrorrhiza Miq |
| title_short | ANTIBACTERIAL ACTIVITY OF XANTHONE FROM ETHYL ACETATE EXTRACT OF THE STEAM BARK OF Garcinia picrorrhiza Miq |
| title_sort | antibacterial activity of xanthone from ethyl acetate extract of the steam bark of garcinia picrorrhiza miq |
| topic | antibacterial Garcinia picrorrhiza Miq xanthone |
| url | https://jurnal.uns.ac.id/alchemy/article/view/4346 |
| work_keys_str_mv | AT muharnimuharni antibacterialactivityofxanthonefromethylacetateextractofthesteambarkofgarciniapicrorrhizamiq AT elfitaelfita antibacterialactivityofxanthonefromethylacetateextractofthesteambarkofgarciniapicrorrhizamiq AT emilpertiwi antibacterialactivityofxanthonefromethylacetateextractofthesteambarkofgarciniapicrorrhizamiq |