Antinociceptive Potential of <i>Ximenia americana</i> L. Bark Extract and Caffeic Acid: Insights into Pain Modulation Pathways

Antinociceptive Potential of <i>Ximenia americana</i> L. Bark Extract and Caffeic Acid: Insights into Pain Modulation Pathways

<b>Background/Objectives:</b> This study evaluated the antinociceptive effect of the <i>Ximenia americana</i> L. bark extract (HEXA) and its primary component, caffeic acid (CA), through in vivo assays. <b>Methods</b>: The antinociceptive properties were assessed...

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Bibliographic Details
Main Authors: Renata Torres Pessoa, Lucas Yure Santos da Silva, Isabel Sousa Alcântara, Tarcísio Mendes Silva, Eduardo dos Santos Silva, Roger Henrique Sousa da Costa, Aparecida Barros da Silva, Jaime Ribeiro-Filho, Anita Oliveira Brito Pereira Bezerra Martins, Henrique Douglas Melo Coutinho, Jean Carlos Pereira Sousa, Andréa Rodrigues Chaves, Ricardo Neves Marreto, Irwin Rose Alencar de Menezes
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pharmaceuticals
Subjects:
natural compounds
HPLC
nociception
anti-inflammatory
mechanism of action
pain
Online Access:https://www.mdpi.com/1424-8247/17/12/1671
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