Mechanisms and reversibility of nicotine-induced spermatogenesis impairment and DNA methylation changes
Abstract Smoking among men of childbearing age poses a significant threat to their reproductive health. Nicotine, the primary bioactive compound in tobacco, adversely affects sperm characteristics, but mechanisms underlying its effects and if these effects are reversible upon cessation are unclear....
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| Main Authors: | Jiajun Cui, Chenglu Wang, Yuxuan Zheng, Yu Zhang, Sisi Luo, Zhuoran Ren, Xueyun Qin, Mo Zhang, Fang Gao, Hefeng Huang, Jing Shu, Guolian Ding |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-025-08493-y |
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