Mechanisms and reversibility of nicotine-induced spermatogenesis impairment and DNA methylation changes

Abstract Smoking among men of childbearing age poses a significant threat to their reproductive health. Nicotine, the primary bioactive compound in tobacco, adversely affects sperm characteristics, but mechanisms underlying its effects and if these effects are reversible upon cessation are unclear....

Full description

Saved in:
Bibliographic Details
Main Authors: Jiajun Cui, Chenglu Wang, Yuxuan Zheng, Yu Zhang, Sisi Luo, Zhuoran Ren, Xueyun Qin, Mo Zhang, Fang Gao, Hefeng Huang, Jing Shu, Guolian Ding
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08493-y
Tags: Add Tag
No Tags, Be the first to tag this record!