Exploring extracellular vesicles as novel therapeutic agents for intervertebral disc degeneration: delivery, applications, and mechanisms

Exploring extracellular vesicles as novel therapeutic agents for intervertebral disc degeneration: delivery, applications, and mechanisms

Abstract Intervertebral disc degeneration is a multifactorial degenerative disease that poses a significant threat to the health of the elderly population. Current treatments primarily focus on physical therapy, medication, and surgery to alleviate symptoms associated with disc compression but do no...

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Main Authors: Yuxin Jin, Ouqiang Wu, Zhihua Chen, Linjie Chen, Kai Zhang, Qizhu Chen, Haijun Tian, Xinzhou Wang, Morgan Jones, Kenny Yat Hong Kwan, Yan Michael Li, Pooyan Makvandi, Xiangyang Wang, Xiang Hai, Jun Zhang, Aimin Wu
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Stem Cell Research & Therapy
Subjects:
Intervertebral disc degeneration
Lower back pain
Extracellular vesicles
Exosomes
Online Access:https://doi.org/10.1186/s13287-025-04299-1
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https://doi.org/10.1186/s13287-025-04299-1

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