Genetic factors shaping the plasma lipidome and the relations to cardiometabolic risk in children and adolescentsResearch in context

Genetic factors shaping the plasma lipidome and the relations to cardiometabolic risk in children and adolescentsResearch in context

Summary: Background: Lipid species are emerging as biomarkers for cardiometabolic risk in both adults and children. The genetic regulation of lipid species and their impact on cardiometabolic risk during early life remain unexplored. Methods: Using mass spectrometry-based lipidomics, we measured 22...

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Main Authors: Yun Huang, Sara Elizabeth Stinson, Malte Thodberg, Louise Aas Holm, Roman Thielemann, Karolina Sulek, Morten Asp Vonsild Lund, Cilius Esmann Fonvig, Min Kim, Kajetan Trost, Helene Bæk Juel, Trine Nielsen, Peter Rossing, Maja Thiele, Aleksander Krag, Cristina Legido-Quigley, Jens-Christian Holm, Torben Hansen
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:EBioMedicine
Subjects:
Lipidomics
Genome-wide association study
Children
Cardiometabolic risk
Mendelian randomisation
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396424005735
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