Spatially-resolved analyses of muscle invasive bladder cancer microenvironment unveil a distinct fibroblast cluster associated with prognosis

Spatially-resolved analyses of muscle invasive bladder cancer microenvironment unveil a distinct fibroblast cluster associated with prognosis

BackgroundMuscle-invasive bladder cancer (MIBC) is a prevalent cancer characterized by molecular and clinical heterogeneity. Assessing the spatial heterogeneity of the MIBC microenvironment is crucial to understand its clinical significance.MethodsIn this study, we used imaging mass cytometry (IMC)...

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Main Authors: Chao Feng, Yaobang Wang, Wuyue Song, Tao Liu, Han Mo, Hui Liu, Shulin Wu, Zezu Qin, Zhenxing Wang, Yuting Tao, Liangyu He, Shaomei Tang, Yuanliang Xie, Qiuyan Wang, Tianyu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
MIBC
tumor microenvironment
spatial heterogeneity
single-cell omics
fibroblast
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1522582/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1522582/full

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