Therapeutic advances in the targeting of ROR1 in hematological cancers

Therapeutic advances in the targeting of ROR1 in hematological cancers

Abstract Receptor tyrosine kinases (RTKs) are key cell surface receptors involved in cell communication and signal transduction, with great importance in cell growth, differentiation, survival, and metabolism. Dysregulation of RTKs, such as EGFR, VEGFR, HER2 or ROR, could lead to various diseases, p...

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Main Authors: Adrian-Bogdan Tigu, Raluca Munteanu, Cristian Moldovan, Drula Rares, David Kegyes, Radu Tomai, Vlad Moisoiu, Gabriel Ghiaur, Ciprian Tomuleasa, Hermann Einsele, Diana Gulei, Carlo M. Croce
Format: Article
Language:English
Published: Nature Publishing Group 2024-11-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-02239-1
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https://doi.org/10.1038/s41420-024-02239-1

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